The purpose of this paper is to report the longitudinal experience with dea
ths in a United States' newborn intensive care unit. Retrospective analysis
comparing infant deaths in two epochs: Epoch 1: 1985-1988 (n = 127) and Ep
och 2: 1991-1994 (n = 75). Data included demographic factors, age at death,
episodes of cardiopulmonary resuscitation, do not resuscitate status, and
whether withdrawal of support occurred. Infants in Epoch 2 were significant
ly younger at birth (28.7 +/- 0.7 vs. 30.6 +/- 0.5 wks', p = 0.02) and deat
h (31.5 +/- 0.9 vs. 34.0 +/- 0.7 wks', p = 0.02) than those in Epoch 1. The
re was no difference in length of stay (19.5 +/- 5.1 vs. 24.4 +/- 4.2 days,
Epoch 2 vs. Epoch 1). Infants were more likely to receive cardiopulmonary
resuscitation in Epoch 2 than Epoch 1 (60 vs. 41%, p = 0.008). However, mor
e infants in Epoch 2 also had do not resuscitate status (80% vs. 59%, p = 0
.002) or withdrawal of support (72% vs. 52%, p = 0.005). The majority of ne
wborn intensive care deaths currently occur with do not resuscitate status
and/or withdrawal of support.