The purpose of this study is to identify factors that predict outcome after
intervention for early (<30 days) infrainguinal graft thrombosis. We revie
wed the medical records, arteriograms, and follow-up studies of patients wh
o underwent infrainguinal bypass for limb salvage between 8/91 and 9/98 and
whose graft failed <30 days from the index procedure. Five factors were an
alyzed: (1) conduit: single segment saphenous vein versus alternative vein
or composite conduit (20 vs. 13 patients); (2) repair modality: constructio
n of a new graft at the time of the initial take-back procedure versus loca
l revision and/or thrombectomy alone (12 vs. 21 patients); (3) run-off: goo
d run-off versus poor run-off (20 vs. 13 patients); (4) operative findings:
the presence of a correctable problem versus noncorrectable problem (20 vs
. 13 patients); and (5) surgical history: previous Versus no previous ipsil
ateral bypass (16 vs. 17 patients). These variables are statistically signi
ficant risk factors that can be used in combination to predict outcome. Unl
ess a focal lesion clearly responsible for graft occlusion is found, comple
te graft replacement should be considered even if the new bypass must be pr
osthetic. The costs and morbidity of repeated procedures argue for primary
amputation when adverse risk factors exist. DOI: 10.1007/s100169910080.