This study's main goal is to test the broad specificity of generalized anxi
ety disorder (GAD) symptom and process variables. These variables were comp
ared in four groups of participants: (1) 24 patients with primary GAD, (2)
24 patients with secondary GAD, (3) 38 other anxiety disorder patients, and
(4) 20 nonclinical control subjects. Each participant received a structure
d diagnostic interview and a series of standardized questionnaires. The res
ults show that DSM-IV GAD symptoms (worry, GAD physical symptoms, and inter
ference due to worry and anxiety) distinguish GAD patients from those with
other anxiety disorders. Two process variables, problem orientation and int
olerance of uncertainty, also differentiated GAD patients from other anxiet
y disorder patients. Overall, these results support the DSM-IV definition o
f GAD and the broad specificity of problem orientation and intolerance of u
ncertainty as GAD process variables.