Solid phase synthesis of aminoboronic acids: Potent inhibitors of the hepatitis C virus NS3 proteinase

Authors
Dunsdon, RM Greening, JR Jones, PS Jordan, S Wilson, FX
Citation
Rm. Dunsdon et al., Solid phase synthesis of aminoboronic acids: Potent inhibitors of the hepatitis C virus NS3 proteinase, BIOORG MED, 10(14), 2000, pp. 1577-1579
Citations number
8
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
10
Issue
14
Year of publication
2000
Pages
1577 - 1579
Database
ISI
SICI code
0960-894X(20000717)10:14<1577:SPSOAA>2.0.ZU;2-J
Abstract
Use of a resin bound diol as a boronic acid protecting group has been devel oped to allow the parallel synthesis of potent inhibitors of the hepatitis C virus NS3 serine proteinase. (C) 2000 Elsevier Science Ltd. All rights re served.