We report a 52-year-old patient with cutaneous angiomas on the trunk in ass
ociation with angiotropic lymphoma involving the nervous system. The lesion
al skin showed proliferation of atypical B cells in the capillaries. The di
agnosis of angiotropic lymphoma with neurological deficits is often difficu
lt before death. Thus, skin biopsy in this case proved to be diagnostic of
the central nervous system disease without the risk of brain biopsy. The di
agnosis of angiotropic lymphoma in the future may be achievable by biopsy o
f coincidental angiomas.