Understanding the insertion of transporters and other membrane proteins

Authors
Dalbey, RE Chen, MY Jiang, FL Samuelson, JC
Citation
Re. Dalbey et al., Understanding the insertion of transporters and other membrane proteins, CURR OP CEL, 12(4), 2000, pp. 435-442
Citations number
59
Categorie Soggetti
Cell & Developmental Biology
Journal title
CURRENT OPINION IN CELL BIOLOGY
ISSN journal
09550674 → ACNP
Volume
12
Issue
4
Year of publication
2000
Pages
435 - 442
Database
ISI
SICI code
0955-0674(200008)12:4<435:UTIOTA>2.0.ZU;2-1
Abstract
Recent studies show that transporters integrate into the lipid bilayer usin g topogenic sequences present throughout the entire polypeptide chain. Thes e topogenic sequences can act in unpredictable ways with new translocation/ stop transfer activities. In addition, a new membrane-insertion pathway has been identified in bacteria with homologs in mitochondria and chloroplasts .