Lipid trafficking and sorting: how cholesterol is filling gaps

Authors
Hoekstra, D van IJzendoorn, SCD
Citation
D. Hoekstra et Scd. Van Ijzendoorn, Lipid trafficking and sorting: how cholesterol is filling gaps, CURR OP CEL, 12(4), 2000, pp. 496-502
Citations number
49
Categorie Soggetti
Cell & Developmental Biology
Journal title
CURRENT OPINION IN CELL BIOLOGY
ISSN journal
09550674 → ACNP
Volume
12
Issue
4
Year of publication
2000
Pages
496 - 502
Database
ISI
SICI code
0955-0674(200008)12:4<496:LTASHC>2.0.ZU;2-U
Abstract
Recent research has highlighted a role for cholesterol homeostasis in the r egulation of trafficking and sorting of sphingolipids. This sorting may dic tate the nature of the acyl chain species of phospholipids in the plasma me mbrane which, in turn, may govern the selective partitioning of these lipid s into lateral domains. Recently, several proteins have been identified tha t play a role in the flow and sorting of all major lipid classes.