The role of calbindin and 1,25dihydroxyvitamin D-3 in the kidney

Authors
Sooy, K Kohut, J Christakos, S
Citation
K. Sooy et al., The role of calbindin and 1,25dihydroxyvitamin D-3 in the kidney, CURR OP NEP, 9(4), 2000, pp. 341-347
Citations number
55
Categorie Soggetti
Urology & Nephrology
Journal title
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
ISSN journal
10624821 → ACNP
Volume
9
Issue
4
Year of publication
2000
Pages
341 - 347
Database
ISI
SICI code
1062-4821(200007)9:4<341:TROCA1>2.0.ZU;2-8
Abstract
The identification of a putative apical Ca++ channel in 1,25-dihydroxyvitam in D-3 responsive epithelia (proximal intestine and the distal nephron) as well as recent studies using calbindin-D-28k knock-out mice indicating the first direct in-vivo evidence for a role for this calcium-binding protein i n renal calcium absorption suggest mechanisms, which had remained incomplet e, related to the control of renal calcium absorption. Curr Opin Nephrol Hy pertens 9:341-347. (C) 2000 Lippincott Williams & Wilkins.