Parathyroid hormone-related peptide and Indian hedgehog

Authors
Chung, UI Kronenberg, HM
Citation
Ui. Chung et Hm. Kronenberg, Parathyroid hormone-related peptide and Indian hedgehog, CURR OP NEP, 9(4), 2000, pp. 357-362
Citations number
54
Categorie Soggetti
Urology & Nephrology
Journal title
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
ISSN journal
10624821 → ACNP
Volume
9
Issue
4
Year of publication
2000
Pages
357 - 362
Database
ISI
SICI code
1062-4821(200007)9:4<357:PHPAIH>2.0.ZU;2-J
Abstract
Normal endochondral bone development requires temporal and spatial coordina tion of various cell types. Parathyroid hormone-related peptide and Indian hedgehog interact with each other and form a feedback loop that plays a maj or role in this coordination. Defects in the signalling of either of the tw o molecules cause severe bone malformations. Curr Opin Nephrol Hypertens 9: 357-362, (C) 2000 Lippincott Williams & Wilkins.