Tandem Michael-Wittig-Horner reaction: One-pot synthesis of delta-substituted alpha,beta-unsaturated carboxylic acid derivatives - Application to a concise synthesis of (Z)- and (E)-ochtoden-1-al

A nerv tandem Michael-Wittig-Horner reaction has been developed to produce in high yields S-substituted alpha,beta-unsaturated esters, amides and lact ones. The reaction has been successfully applied to a concise synthesis of (E)- and (Z)-ochtoden-1-als, components of the male sex pheromone of bell w eevil from 3-methylcyclohex-2-en-1-one.