M. De Santis et al., Congenital cystic adenomatoid malformation of the lung: Antenatal ultrasound findings and fetal-neonatal outcome - Fifteen years of experience, FETAL DIAGN, 15(4), 2000, pp. 246-250
Seventeen cases of congenital cystic adenomatoid malformation of the lung (
CCAM) are reported. They were followed up over a period of 1 month to 15 ye
ars. Diagnosis was made by prenatal ultrasound. Our purpose was to evaluate
the fetal-neonatal outcome and the prognostic elements observable through
ultrasound techniques, and to compare all types of CCAM. The outcome observ
ed ranged from total prenatal resolution to postnatal spontaneous regressio
n of the lesion, to complications due to the presence of nonimmune fetal hy
drops (NIFH), intrauterine death and the necessity of surgical intervention
. In our experience only hydrops represented a negative predictor of outcom
e since death occurred in all cases with this pathology. In the absence of
NIFH, counselling should stress the prevalence of a positive outcome, even
in cases of surgical intervention. Copyright (C) 2000 S. Karger AG. Basel.