Formation of plasmin-like and activator proteinases by Bacillus firmus
cells immobilized in polyacrylamide gel was studied. Immobilized cell
s were shown to differ from free cells by a higher rate of enzyme synt
hesis and a longer period of high-level enzyme production. The total p
lasmin-like activity and activator activity increased 2.6- and S-fold,
respectively; the stability of the system was enhanced 2-fold; and th
e affinity of the proteinase complex to fibrin and plasminogen increas
ed 1.5-fold.