Citation
V. Murugan et al., Synthesis and estrogenic screening of some new quinazolinonyl triazoles, I J HET CHE, 9(4), 2000, pp. 267-270
Citations number
16
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
09711627
→ ACNP
Volume
9
Issue
4
Year of publication
2000
Pages
267 - 270
Database
ISI
SICI code
0971-1627(200004/06)9:4<267:SAESOS>2.0.ZU;2-I
Abstract
Four new quinazolinone derivatives of 6,8-dibromo-2-methyl-3-[3-mercapto-4-
(4-phenyl/substituted phenyl)-4(H)-1,2,4-triazol-5-yl-methyl amino]-quinazo
lin-4(3H) ones were synthesized and characterized by their spectral and ana
lytical data: All compounds could inhibit the oxytocin-induced rat uterus c
ontractions, however, with a degree of variation. Particularly, compounds V
a and Vb produced significant relaxation on rat uterus muscle.