Studies on antitubercular agents: Synthesis of 4-pyridoyl-3-substituted-1,2,4-triazolo (3,4-b) (1,3,4)-thiadiazolidines

Authors
Udupi, RH Purushottamachar, P Bhat, AR
Citation
Rh. Udupi et al., Studies on antitubercular agents: Synthesis of 4-pyridoyl-3-substituted-1,2,4-triazolo (3,4-b) (1,3,4)-thiadiazolidines, I J HET CHE, 9(4), 2000, pp. 287-290
Citations number
13
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
09711627 → ACNP
Volume
9
Issue
4
Year of publication
2000
Pages
287 - 290
Database
ISI
SICI code
0971-1627(200004/06)9:4<287:SOAASO>2.0.ZU;2-#
Abstract
Syntheses and in-vitro antitubercular and antiinflammatory activities of no vel series of 4-pyridoyl-3-substituted-1,2,4-triazolo (3,4-b) (1,3,4) thiad iazolidines (3a-o) from 2 and formaldehyde are described. The compounds 3a, 3c,3d, 3f, 3i, 3j, 3k, 3l, 3m and 3o exhibited significant antitubercular a ctivity. It was interesting to note that 3b showed antiinflammatory profile .