Brain tissues from both sides of the cerebellum and frontal, temporal, pari
etal, and occipital lobes were collected postmortem from 30 patients for hu
man herpesvirus 8 (HHV-8) detection by PCR. Overall, 42 of 300 (14.0%) samp
les were positive, with similar rates for each position. Nineteen patients
(63.3%) were positive and showed a significant increase in positivity with
age (P = 0.007), The results indicate a neuroinvasive and neuropersistent p
otential of HHV-8.