Physical and chemical characteristics of dietary ingredients and their inte
ractions can have a large effect on dry matter intake (DMI) of lactating co
ws. Physical limitations caused by distension of the reticulo-rumen or othe
r compartments of the gastrointestinal tract of ten limit DMI of high produ
cing cows or cows fed high forage diets. Fermentation acids also limit DMI
from a combination of increased osmolality in the reticulorumen and specifi
c effects of propionate, although the mechanisms are not clear. The specifi
c physical and chemical characteristics of diets that can affect DMI includ
e fiber content, ease of hydrolysis of starch and fiber, particle size, par
ticle fragility, silage fermentation products, concentration and characteri
stics of fat, and the amount and ruminal degradation of protein. Site of st
arch digestion affects the form of metabolic fuel absorbed, which can affec
t DMI because absorbed propionate appears to be more hypophagic than lactat
e or absorbed glucose. Dry matter intake is likely determined by integratio
n of signals in brain satiety centers. Difficulty in measurement and extens
ive interactions among the variables make it challenging to account for die
tary effects when predicting DMI. However, a greater understanding of the m
echanisms along with evaluation of animal responses to diet changes allows
diet adjustments to be made to optimize DMI as well as to optimize allocati
on of diet ingredients to animals. This paper discusses some of the charact
eristics of dietary ingredients that should be considered when formulating
diets for lactating dairy cows and when allocating feeds to different group
s of animals on the farm.