Exercise treadmill electrocardiography and myocardial perfusion imaging are
commonly used in non-invasive tests for the detection of myocardial ischae
mia. Unfortunately there are limitations in the assessment of hypertensive
patients since these tests frequently provide false-positive results, parti
cularly in those subjects with left ventricular hypertrophy, In order to in
vestigate the utility of stress echocardiography in hypertensive patients w
e assessed 173 subjects undergoing this investigation in our department. Of
these, 66 had had coronary angiography within 6 months. Thirty subjects we
re hypertensives, 17 with left ventricular hypertrophy, and 36 normotensive
s. Patients with a 70% or greater stenosis at coronary angiography were dee
med to have sufficient disease to cause myocardial ischaemia, The overall s
ensitivity of stress echocardiography for detecting myocardial ischaemia wa
s 83% with a specificity of 77%. For the hypertensive group alone the sensi
tivity was 93% and specificity 73%, The normotensives had a sensitivity of
76% with a specificity of 80%, In conclusion, in this group of hypertensive
s stress echocardiography had a favourable specificity and this was not sig
nificantly different from that of normotensive subjects.