The chronobiology of blood pressure is a useful tool for examining serial d
ata to quantify the dynamics of variability. The implications and applicati
ons for diagnosis and therapy are discussed, with clinical examples. The ch
ronobiological patterns of hypertension are described.
Chronobiology can make a real contribution to the prevention of disease.Chr
onobiology helps diagnose circadian hyper-amplitude-tension (CHAT), a condi
tion in which excessive circadian BP amplitude precedes chronic established
hypertension.