Acute enlargement and subsequent rupture of an abdominal aortic aneurysm in a patient receiving chemotherapy for pancreatic carcinoma

Citation
Sj. Palm et al., Acute enlargement and subsequent rupture of an abdominal aortic aneurysm in a patient receiving chemotherapy for pancreatic carcinoma, J VASC SURG, 32(1), 2000, pp. 197-200
Citations number
31
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
JOURNAL OF VASCULAR SURGERY
ISSN journal
07415214 → ACNP
Volume
32
Issue
1
Year of publication
2000
Pages
197 - 200
Database
ISI
SICI code
0741-5214(200007)32:1<197:AEASRO>2.0.ZU;2-V
Abstract
We report a case of ruptured abdominal aortic aneurysm (AAA) in a patient r eceiving chemotherapy for pancreatic cancer. We reviewed the literature on the effects of corticosteroids and chemotherapy on AAA formation and discus s possible mechanisms for drug action to promote aneurysm expansion and rup ture. If cancer and AAA coincide and curative chemotherapy is possible, a p otential impact of chemotherapy on AAA expansion should be considered.