Expression analysis of classic and non-classic HLA molecules before interferon alfa-2b treatment of melanoma

Authors
Wagner, SN Rebmann, V Willers, CP Grosse-Wilde, H Goos, M
Citation
Sn. Wagner et al., Expression analysis of classic and non-classic HLA molecules before interferon alfa-2b treatment of melanoma, LANCET, 356(9225), 2000, pp. 220-221
Citations number
5
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
LANCET
ISSN journal
01406736 → ACNP
Volume
356
Issue
9225
Year of publication
2000
Pages
220 - 221
Database
ISI
SICI code
0140-6736(20000715)356:9225<220:EAOCAN>2.0.ZU;2-A
Abstract
Individual predictive clinical, immunological, or molecular features for de finition of patients with lymph-node-positive melanoma who do not benefit f rom adjuvant postsurgery high-dose interferon alfa treatment are lacking. E xpression analysis of classic and non-classic HLA molecules on melanoma cel ls metastatic to the locoregional lymph node may help select these patients before treatment.