SOX8 expression during chick embryogenesis

We have isolated the SOX8 gene from the chicken embryo. This gene shows a h igh degree of sequence homology to SOX9 and SOX10. Detailed analysis of SOX 8 expression by whole-mount in situ shows a dynamic and restricted expressi on pattern during chick development. SOX8 is expressed in the semitic deriv ative, the dermomyotome, the developing heart, pancreas, enteric neurone sy stem, limb and the neural tube. This is the first detailed expression analy sis of SOX8 in any species (C) 2000 Elsevier Science Ireland Ltd. All right s reserved.