Context Time preference (how preference for an outcome changes depending on
when the outcome occurs) affects clinical decisions, but little is known a
bout determinants of time preferences in clinical settings. Objectives. To
determine whether information about mean population time preferences for sp
ecific health states can be easily assessed, whether mean time preferences
are constant across different diseases, and whether under certain circumsta
nces substantial fractions of the patient population make choices that are
consistent with a negative time preference. Design. Self-administered surve
y. Setting. Family physician waiting rooms in four states. Patients. A conv
enience sample of 169 adults. Intervention. Subjects were presented five cl
inical vignettes. For each vignette the subject chose between interventions
maximizing a present and a future health outcome. The options for individu
al vignettes varied among the patients so that a distribution of responses
was obtained across the population of patients. Main outcome measure. Logis
tic regression was used to estimate the mean preference for each vignette,
which was translated into an implicit discount rate for this group of patie
nts. Results. There were marked differences in time preferences for future
health outcomes based on the five vignettes, ranging from a negative to a h
igh positive (116%) discount rate. Conclusions. The study provides empirica
l evidence that time preferences for future health outcomes may vary substa
ntially among disease conditions. This is likely because the vignettes evok
ed different rationales for time preferences. Time preference is a critical
element in patient decision making and cost-effectiveness research, and mo
re work is necessary to improve our understanding of patient preferences fo
r future health outcomes.