Acidic ribosomal proteins and histone H3 from Leishmania present a high rate of divergence

Citation
Y. Montoya et al., Acidic ribosomal proteins and histone H3 from Leishmania present a high rate of divergence, MEM I OSW C, 95(4), 2000, pp. 591-594
Citations number
12
Categorie Soggetti
Medical Research General Topics
Journal title
MEMORIAS DO INSTITUTO OSWALDO CRUZ
ISSN journal
00740276 → ACNP
Volume
95
Issue
4
Year of publication
2000
Pages
591 - 594
Database
ISI
SICI code
0074-0276(200007/08)95:4<591:ARPAHH>2.0.ZU;2-P
Abstract
Another additional peculiarity in Leishmania will be discussed about of the amino acid divergence rate of three structural proteins: acidic ribosomal PI and P2b proteins, and histone H3 by using multiple sequence alignment an d dendrograms. These structural proteins present a high rate of divergence regarding to th eir homologous protein in Trypanosoma cruzi. At this regard, L. (V.) peruvi ana PI and T. cruzi PI showed 57.4% of divergence rate. Likewise, L. (V.) b raziliensis histone H3 and acidic ribosomal P2 protein exhibited 31.8% and 41.7% respectively of rate of divergence in comparison with their homologou s Bz T. cruzi.