Sharing calcium opens new avenues of signalling

Authors
Citation
Ap. Thomas, Sharing calcium opens new avenues of signalling, NAT CELL BI, 2(7), 2000, pp. E126-E128
Citations number
12
Categorie Soggetti
Cell & Developmental Biology
Journal title
NATURE CELL BIOLOGY
ISSN journal
14657392 → ACNP
Volume
2
Issue
7
Year of publication
2000
Pages
E126 - E128
Database
ISI
SICI code
1465-7392(200007)2:7<E126:SCONAO>2.0.ZU;2-0
Abstract
A consequence of intracellular calcium signalling is that calcium released into the cytosol is extruded from the cell. New research shows that when th e interstitial space is constricted, calcium extruded from one cell may inc rease levels of calcium in the surrounding medium sufficiently to activate calcium-sensing receptors on the surfaces of adjacent cells. Thus, the calc ium that serves as an intracellular signal can also serve as an extracellul ar signal to recruit neighbouring cells.