Response of leptomeningeal metastases from breast cancer to hormonal therapy

Authors
Boogerd, W Dorresteijn, LDA van der Sande, JJ de Gast, GC Bruning, PF
Citation
W. Boogerd et al., Response of leptomeningeal metastases from breast cancer to hormonal therapy, NEUROLOGY, 55(1), 2000, pp. 117-119
Citations number
10
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
55
Issue
1
Year of publication
2000
Pages
117 - 119
Database
ISI
SICI code
0028-3878(20000712)55:1<117:ROLMFB>2.0.ZU;2-U
Abstract
Intraventricular chemotherapy with radiotherapy is the standard treatment o f leptomeningeal metastasis (LM) from breast cancer; this treatment increas es median survival only to about 3 months and is frequently complicated by serious side effects. The authors describe two patients with LM from breast cancer who were treated with hormonal therapy, which provided a neurologic response of at least 12 months and a survival of 14+ and 19 months. Hormon al therapy can be effective and nontoxic for patients with LM from breast c ancer.