Sonic detection system for cervical and intracranial vascular disease

A sonic analysis system was developed for the detection of cervical and int racranial vascular disease (CVD). In this study, sound signals detected thr ough the patient's forehead were analyzed using a short-time Fourier transf ormation method, and data were evaluated according to the intensity of spec tra. A total of 49 patients with CVD and 34 control subjects were studied a nd classified into four grades according to the intensity of the spectra. T he true positive rate was 83.7% in patients with CVD, and the true negative rate was 94.1% in the control group. The sensitivity and specificity of th is analysis system were 83.7% and 5.9%, respectively. The true positive rat es for cerebral stenosis/occlusion, cerebral aneurysm, and arteriovenous ma lformation/fistula were 85.7%, 73.7%, and 100%, respectively. The future go al is clinical application as a mass-screening test for brain disease. This system shows potential for this purpose, and further development will cont inue.