The theme of this lecture is concerned with the change in behaviour of simp
le molecules which occurs when such molecules are incorporated into assembl
ed or self-assembled mono- and multilayers on surfaces. The area is one of
wide technological importance because of potential application in, for exam
ples, photoresists, piezo and pyroelectric devices, and multiple harmonic o
scillators(1). Behaviour of assembled molecules is also significant because
of the nature of lipid bilayer cell membranes and their behaviour is, of c
ourse, of front-line importance in connection with matters such as inherent
stability and penetration by drugs and so on. This account is concentrated
upon events at the molecular level and the emphasis is on the relationship
between structure and selectivity.