L. Domon et D. Uguen, Toward a total synthesis of stigmatellin; obtention of an advanced fragment from gallic acid, TETRAHEDR L, 41(29), 2000, pp. 5501-5505
Treatment by a base, then an acid, of the ester 3, which was prepared by st
arting from gallic acid 7a, afforded the chromone 6c, whose Swern oxidation
, followed by condensation of the resulting aldehyde 6a with the trienyl li
thium derivative 13b and methyl iodide, furnished products isomeric with, b
ut not strictly identical to, an authentic sample of O-benzyl stigmatellin
Ic. (C) 2000 Elsevier Science Ltd. All rights reserved.