Palladium-catalyzed synthesis of stereodefined 3-[(1,1-unsymmetrically disubstituted)methylidene]isobenzofuran-1(3H)-ones and stereodefined 5-[(1,1-unsymmetrically disubstituted)methylidene]furan-2(5H)-ones

Authors
Rossi, R Bellina, F Biagetti, M Catanese, A Mannina, L
Citation
R. Rossi et al., Palladium-catalyzed synthesis of stereodefined 3-[(1,1-unsymmetrically disubstituted)methylidene]isobenzofuran-1(3H)-ones and stereodefined 5-[(1,1-unsymmetrically disubstituted)methylidene]furan-2(5H)-ones, TETRAHEDR L, 41(27), 2000, pp. 5281-5286
Citations number
23
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
27
Year of publication
2000
Pages
5281 - 5286
Database
ISI
SICI code
0040-4039(20000701)41:27<5281:PSOS3D>2.0.ZU;2-#
Abstract
Treatment of (hetero)aryl halides with 2-(1-alkynyl)benzoic acids or (Z)-2- en-4-ynoic acids in the presence of K2CO3 and a catalytic amount of Pd(PPh3 )(4) provides reaction mixtures in which stereodefined 3-[(1,1-unsymetrical ly disubstituted)methylidene]isobenzofuran-1(3H)-ones and stereodefined 5-[ (1,1-unsymmetrically disubstituted)methylidene]furan-2(5H)-ones respectivel y, are the major products. (C) 2000 Elsevier Science Ltd. All rights reserv ed.