The mammalian fatty acid-binding protein multigene family: Molecular and genetic insights into function

Authors
Hertzel, AV Bernlohr, DA
Citation
Av. Hertzel et Da. Bernlohr, The mammalian fatty acid-binding protein multigene family: Molecular and genetic insights into function, TRENDS ENDO, 11(5), 2000, pp. 175-180
Citations number
54
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
TRENDS IN ENDOCRINOLOGY AND METABOLISM
ISSN journal
10432760 → ACNP
Volume
11
Issue
5
Year of publication
2000
Pages
175 - 180
Database
ISI
SICI code
1043-2760(200007)11:5<175:TMFAPM>2.0.ZU;2-Q
Abstract
Intracellular fatty acid-binding proteins associate with fatty acids and ot her hydrophobic biomolecules in an internal cavity, providing for solubiliz ation and metabolic trafficking. Analyses of their in vivo function by mole cular and genetic techniques reveal specific function(s) that fatty acid-bi nding proteins perform with respect to fatty acid uptake, oxidation and ove rall metabolic homeostasis.