Av. Hertzel et Da. Bernlohr, The mammalian fatty acid-binding protein multigene family: Molecular and genetic insights into function, TRENDS ENDO, 11(5), 2000, pp. 175-180
Intracellular fatty acid-binding proteins associate with fatty acids and ot
her hydrophobic biomolecules in an internal cavity, providing for solubiliz
ation and metabolic trafficking. Analyses of their in vivo function by mole
cular and genetic techniques reveal specific function(s) that fatty acid-bi
nding proteins perform with respect to fatty acid uptake, oxidation and ove
rall metabolic homeostasis.