Senescence is the last stage of leaf development and one type of programmed
cell death that occurs in plants. The relationships among senescence progr
ams that are induced by a variety of factors have been addressed at a molec
ular level in recent studies. Furthermore, an overlap between the pathogen-
response and senescence programs is beginning to be characterized. The comp
lexity of the senescence program is also evident in studies of senescence-s
pecific gene regulation and the role of photosynthesis and plant hormones i
n senescence regulation. New molecular-genetic approaches are expected to b
e useful in unraveling the molecular mechanisms of the leaf senescence prog
ram.