The increased number of vaginal yeast infections in the past few years has
been a disturbing trend, and the scientific community has been searching fo
r its etiology. Several theories have been put forth to explain the apparen
t increase. First, the; recent widespread availability of low-dosage, azole
-based, over-the-counter antifungal medications for vaginal yeast infection
s encourages women to self-diagnose and treat, and women may be misdiagnosi
ng themselves. Their vaginitis may be caused by bacteria, parasites or may
be a symptom of another underlying health condition. As a result, they may
be unnecessarily and chronically expose themselves to antifungal medication
s and encourage fungal resistance. Second, medical technology has increased
the life span of seriously immune compromised individuals, yet these indiv
iduals are frequently plagued by opportunistic fungal infections. Long-term
and intense azole-based antifungal treatment has been linked to an increas
e in resistant Candida and non-Candida species. Thus, the future of limitin
g antifungal resistance lies in identifying the factors promoting resistanc
e and implementing policies to prevent it.