Antifungal resistance in yeast vaginitis

Authors
Citation
E. Dun, Antifungal resistance in yeast vaginitis, YALE J BIOL, 72(4), 1999, pp. 281-285
Citations number
15
Categorie Soggetti
Medical Research General Topics
Journal title
YALE JOURNAL OF BIOLOGY AND MEDICINE
ISSN journal
00440086 → ACNP
Volume
72
Issue
4
Year of publication
1999
Pages
281 - 285
Database
ISI
SICI code
0044-0086(199907/08)72:4<281:ARIYV>2.0.ZU;2-D
Abstract
The increased number of vaginal yeast infections in the past few years has been a disturbing trend, and the scientific community has been searching fo r its etiology. Several theories have been put forth to explain the apparen t increase. First, the; recent widespread availability of low-dosage, azole -based, over-the-counter antifungal medications for vaginal yeast infection s encourages women to self-diagnose and treat, and women may be misdiagnosi ng themselves. Their vaginitis may be caused by bacteria, parasites or may be a symptom of another underlying health condition. As a result, they may be unnecessarily and chronically expose themselves to antifungal medication s and encourage fungal resistance. Second, medical technology has increased the life span of seriously immune compromised individuals, yet these indiv iduals are frequently plagued by opportunistic fungal infections. Long-term and intense azole-based antifungal treatment has been linked to an increas e in resistant Candida and non-Candida species. Thus, the future of limitin g antifungal resistance lies in identifying the factors promoting resistanc e and implementing policies to prevent it.