During screening examinations and, when appropriate, other health-related v
isits, family physicians should be alert. for signs and symptoms of common
psychosocial disorders in men. Health issues of concern include alcohol and
substance abuse, domestic violence, midlife crisis and depression. Alcohol
remains the most abused drug in America. The highest rates of alcohol abus
e are in men 25 to 39 years of age, although alcoholism is also a considera
ble problem after 65 years of age. Disulfiram and the opioid antagonist nal
trexone are the two medications currently labeled by the U.S. Food and Drug
Administration for the treatment of chronic alcohol dependence. Like alcoh
ol abuse, domestic violence is a sign of psychosocial distress in men. Dome
stic violence may be a problem in up to 16 percent of marriages. Most men m
ove through the midlife period without difficulty. Major depressive illness
occurs in about 1 percent of elderly men, whereas minor depression or subs
yndromal depression affects 13 to 27 percent of older men. Selective seroto
nin reuptake inhibitors have become first-line therapy for depression.