Ankylosing vertebral hyperostosis, or hyperostotic disease, is an ossificat
ion of the entheses, the regions of insertion of tendons, ligaments or join
t capsules into the bone. These ossifications create intervertebral bridges
(ossifications of the common anterior, lateral and posterior intervertebra
l ligaments as well as of the ligamentum flavum), which are responsible for
the potential signs of the disease: back and neck pain and stiffness, spin
al cord compression at the cervical level and lumbar canal stenosis at the
lumbar level. The bony epiphyses are the sites of bony appositions, or enth
esophytes, which may compromise joint mobility and increase the risk of sec
ondary osteoarthritis, causing hip and knee disorders in particular. These
degenerative joint diseases may eventually necessitate total replacement. I
n this case, the risk of re-ossification around the prosthesis must be aver
ted by the immediate postoperative prescription of anti-inflammatory medica
tion for 1-2 weeks.