Synthetic studies on calicheamicin gamma(1) - synthesis of (-)-calicheamicinone and models representing the four sugars and the aromatic system

Authors
Clive, DLJ Tao, Y Bo, YX Hu, YZ Selvakumar, N Sun, SY Daigneault, WS Wu, YJ
Citation
Dlj. Clive et al., Synthetic studies on calicheamicin gamma(1) - synthesis of (-)-calicheamicinone and models representing the four sugars and the aromatic system, CHEM COMMUN, (15), 2000, pp. 1341-1350
Citations number
56
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
15
Year of publication
2000
Pages
1341 - 1350
Database
ISI
SICI code
1359-7345(2000):15<1341:SSOCG->2.0.ZU;2-H
Abstract
The synthesis of (-)-calicheamicinone (2), the carbohydrates 88, 101, 111, 119 and 120, and the hexasubstituted benzene 139, is described; these compo unds formally represent the subunits of the antitumor antibiotic calicheami cin gamma(1)(I) (1).