A prospective study of depot-medroxyprogesterone acetate (DMPA) use in wome
n aged above 35 years was conducted in Bangkok, Thailand. The objectives of
the study were to evaluate efficacy, continuation rate, and side effects o
f DMPA use in these women. A total of 60 women were enrolled in a one-year
clinical trial. Their mean age was 38 years. Most of them had completed pri
mary school. No accidental pregnancies occurred throughout the 1-year use i
n this study. The continuation rate was 20%. Irregular bleeding was the maj
or cause of termination. The major side effect was also irregular bleeding.
Nevertheless, DMPA in older women is a safe and effective contraceptive. D
MPA is a contraceptive akterbatuve fir women aged above 35 with contraindic
ations to combination oral contraceptives. (C) 2000 Elsevier Science Inc. A
ll rights reserved.