We report a case of rhinocerebral mucormycosis presenting in a patient with
AIDS and review the literature on mucormycosis occurring in the setting of
HIV disease. Mucormycosis in HIV is rare. However, it can be the presentin
g opportunistic infection in AIDS. Predisposing factors for Mucor infection
in HIV disease include low CD4 count. neutropenia, and active intravenous
drug use. Mucormycosis can present in the basal ganglia, the skin, the gast
rointestinal tract, the respiratory tract, or may be disseminated. The dise
ase may develop insidiously or may progress rapidly with a fulminant course
. Therapy usually consists of surgical debridement/excision accompanied by
intravenous amphotericin B.