Anal verrucous carcinoma and penile condylomata acuminata

A 50-year-old man presented with recurrent tumorous lesions on the penis an d the anal region. The anal lesion was histologically diagnosed as verrucou s carcinoma (VC) and the penile lesions were in line with condylomata acumi nata. Samples taken from tumors of both sites were human papillomavirus (HP V) DNA positive. Two of them taken from the penis and the perianal region s cored HPV DNA 6 positive by using polymerase chain reaction and the Souther n blot method. Treatment of both VC and condylomata acuminata consisted in surgery and adjuvant immune therapy. Neither tumor recurrence nor metastase s occurred up until 6 months after therapy. Copyright (C) 2000 S. Karger AG , Basel.