Three cases of pityriasis rubra pilaris successfully treated with cyclosporin A

Background: Pityriasis rubra pilaris (PRP) is reported to respond poorly to cyclosporin A (CsA), Objective: We attempted to deter mine the efficacy of CsA in the treatment of classic adult-type PRP, Methods: Three patients wi th classic adult-type PRP were treated with 5 mg/kg/day CsA, Results: A sus tained clinical response was achieved within 2-4 weeks of therapy. Relapses were noted when the CsA dose was decreased to 1.2 mg/kg/day. Conclusion: C sA should be considered in the treatment of classical adult-type PRP. Copyr ight (C) 2000 S. Karger AG, Baser.