Background: Pityriasis rubra pilaris (PRP) is reported to respond poorly to
cyclosporin A (CsA), Objective: We attempted to deter mine the efficacy of
CsA in the treatment of classic adult-type PRP, Methods: Three patients wi
th classic adult-type PRP were treated with 5 mg/kg/day CsA, Results: A sus
tained clinical response was achieved within 2-4 weeks of therapy. Relapses
were noted when the CsA dose was decreased to 1.2 mg/kg/day. Conclusion: C
sA should be considered in the treatment of classical adult-type PRP. Copyr
ight (C) 2000 S. Karger AG, Baser.