Since silicone has rapidly become one of the most commonly used prosthetic
materials in the last 30 years in modern medicine, we have consequently bee
n witnessing more silicone-related disease. Especially after silicone breas
t implantation, defects in the breast implant have led to serious complicat
ions, whereas complications of silicone prosthesis implantation in other bo
dy parts are less frequent. Here we present an unusual clinical presentatio
n of a silicone granuloma in a patient with a 27-year history of a wide exc
ision of a melanoma of the right lower extremity and subsequent soft-tissue
reconstruction using a silicone device. Copyright (C) 2000 S. Karger AG, B
asel.