Aims/hypothesis. To assess the results of the strategy used in avoiding maj
or amputations in patients with diabetes mellitus.
Methods. A retrospective study for the years 1981 to 1995 in a central dist
rict hospital in Copenhagen with a catchment area population of about 178,0
00.
Results. There were 463 major leg amputations and the incidence decreased f
rom 27.2 to 6.9/100,000 population (75 %). The decrease in patients with Ty
pe I (insulin-dependent) diabetes mellitus was from 10.0 to 4.1 (59 %) and
in Type II (non-insulin-dependent) diabetes mellitus from 17.2 to 2.8/100,0
00 people (84 %). Analysis showed that the diabetic population remained con
stant despite a considerable fall in the number of older people. During the
study period infra-popliteal arterial bypass was introduced for the treatm
ent of critical lower limb ischaemia and in diabetic patients the number of
bypasses increased from zero to 13/100,000 population, The total number of
revascularisation procedures in people with diabetes increased from 2.6 to
19.2/ 100,000 population. Moreover, a multidisciplinary diabetic foot clin
ic was established.
Conclusion/interpretation. A 75 % reduction in the incidence of major amput
ations coincided with a sevenfold increase in revascularization procedures
and the establishment of a multidisciplinary diabetic foot clinic suggestin
g these measures are important in the prevention of diabetic leg amputation
s.