The theoretical basis for scaling-up by the use of the method of microwavegranulation

For the scaling-up achieved by the use of the method of wet microwave granu lation based on calculations, there is a need for an exact mathematical des cription for the relationship between the dose of radiation and the resulta nt effect. By assessing the physical, physical-chemical, and chemical facto rs, we may conclude that, by the gross kinetic evaluation of the change in the enthalpy and the loss of humidity, there is a possible solution for the mathematical description of the single-step, single-pot granulation from t he practical aspect of finding ways to scale-up. This paper overviews the e xperiments performed in a laboratory-size microwave vacuum granulator in te sting two different granules with respect to composition and permittivity a nd presents the evaluation of the experimental data.