Prediction of drug solubility in ternary solvent mixture

Authors
Jouyban-Gharamaleki, A Clark, BJ Acree, WE
Citation
A. Jouyban-gharamaleki et al., Prediction of drug solubility in ternary solvent mixture, DRUG DEV IN, 26(9), 2000, pp. 971-973
Citations number
8
Categorie Soggetti
Pharmacology & Toxicology
Journal title
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
ISSN journal
03639045 → ACNP
Volume
26
Issue
9
Year of publication
2000
Pages
971 - 973
Database
ISI
SICI code
0363-9045(2000)26:9<971:PODSIT>2.0.ZU;2-E
Abstract
Applicability of the combined, nearly ideal, binary solvent/Redlich-Kister equation for calculating drug solubility in ternary mixtures is presented T he advantages of the proposed model are discussed and compared with a recen tly published equation that calculates the solute solubility in ternary sol vent mixtures based on the mixture response methodology.