Total percentage body weight changes during add-on therapy with tiagabine,carbamazepine and phenytoin

Authors
Hogan, RE Bertrand, ME Deaton, RL Sommerville, KW
Citation
Re. Hogan et al., Total percentage body weight changes during add-on therapy with tiagabine,carbamazepine and phenytoin, EPILEPSY R, 41(1), 2000, pp. 23-28
Citations number
15
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
EPILEPSY RESEARCH
ISSN journal
09201211 → ACNP
Volume
41
Issue
1
Year of publication
2000
Pages
23 - 28
Database
ISI
SICI code
0920-1211(200008)41:1<23:TPBWCD>2.0.ZU;2-1
Abstract
Changes in body weight were evaluated in 349 patients from a study comparin g efficacy of add-on therapy with tiagabine (TGB), carbamazepine (CBZ) or p henytoin (PHT). TGB add-on therapy showed no significant weight changes whe n added to either PHT or CBZ. CBZ add-on therapy showed a significant perce ntage weight gain of a mean body increase of 1.5% (P = 0.002). Adjunctive T GB therapy had no significant effect on total body weight, while adjunctive CBZ therapy was associated with weight gain. (C) 2000 Elsevier Science B.V . Ali rights reserved.