M. Hubler et al., Combination of balanced and regional anaesthesia for minimally invasive surgery in a patient with myasthenia gravis, EUR J ANAES, 17(5), 2000, pp. 325-328
A 45-year-old man with cryptorchism, who was known to suffer from generaliz
ed myasthenia gravis, was admitted to hospital for surgical treatment using
laparoscopy. Such minimally invasive surgery requires good muscle relaxati
on. However, the use of neuromuscular blocking agents in patients with myas
thenia gravis may lead to prolonged apnoea after operation, thus necessitat
ing mechanical ventilation of the lungs. We used a combination of general a
naesthesia (with desflurane), and epidural anaesthesia (with the amide loca
l anaesthetic ropivacaine) to obtain excellent abdominal relaxation during
surgery. Tracheal extubation was possible immediately after the operation a
nd no adverse effects were observed. The patient was discharged from hospit
al on the second day after operation. The combination of regional and gener
al anaesthesia for minimally invasive surgery in this patient permitted saf
e anaesthetic management.