The value of fine-needle aspiration biopsy in the diagnosis of parotid gland neoplasms

Citation
U. Schroder et al., The value of fine-needle aspiration biopsy in the diagnosis of parotid gland neoplasms, HNO, 48(6), 2000, pp. 421-429
Citations number
31
Categorie Soggetti
Otolaryngology
Journal title
HNO
ISSN journal
00176192 → ACNP
Volume
48
Issue
6
Year of publication
2000
Pages
421 - 429
Database
ISI
SICI code
0017-6192(200006)48:6<421:TVOFAB>2.0.ZU;2-0
Abstract
Background: In many parts of Germany fine-needle aspiration biopsy (FNAB) i s still not part of the routine preoperative diagnostic evaluation of saliv ary gland neoplasms. Most opponents consider the study unnecessary and reco mmend that all salivary gland neoplasms should be excised. Objective: Because of this an evaluated the ability of FNAB to provide an a ccurate diagnosis of parotid gland neoplasms. Patients and method: Between January 1992 and October 1995, 336 patients re ferred for operative therapy of salivary gland neoplasms underwent retrospe ctive analysis of preoperative FNAB compared with the excised tumor histolo gy. Results: Results showed that the FNAB had a sensitivity of 93.1%,a specifit y of 99.2%,a positive predictive value of 93.1%, a negative predictive valu e of 99.2% and an accuracy of 98.6%. Complications were observed in less th an 1%. Discussion: Our findings demonstrated that the FNAB is a safe diagnostic to ol that has a reliable sensitivity and high specificity for the assessment of salivary gland pathology. Since many malignant salivary gland neoplasms present with a virtual lack of symptoms indicating actual malignancy we bel ieve that there is need for FNAB in routine preoperative diagnostic testing .