We introduce a novel hybrid telepathology system providing simultaneous tra
nsmission of both real-time microscopy and static imagery at a reasonable c
ost. It is capable of capturing static, true color images at resolution of
1,520 x 1,144 pixels and providing live transmission of real-time video ima
ges of the glass slide in Common Intermediate Format (CIF), which can be vi
ewed at 1,024 x 768 pixels or higher. Instant freeze function can be enable
d with 4x CIF resolution (1,408 x 1,152 pixels). This system comprises the
advantages of real-time transmission and high-resolution static imagery, wh
ile direct visual and audio communications are maintained at the same time.
It uses standard 'off-the-shelf' components with a total cost of around $3
0,000 to $40,000. We also conclude that differences in telepathology modali
ty and image quality have an impact on diagnostic accuracy and should be co
nsidered for discussion and standards development by professional organizat
ions in the field of telepathology. An effort to ascertain the diagnostic l
imitations of various telepathology modalities is essential to the future u
se of this modality of pathology practice. Copyright (C) 2000 by W.B. Saund
ers Company.