Vasculogenic impotence and cavernosal oxygen tension

Aims of this study: To determine the associations, if any, of cavernosal ox ygen tension with vasculogenic impotence. Materials and Methods: We evaluated penile cavernosal blood gas levels in m en with suspected vasculogenic impotence during penile duplex ultrasonograp hy and/or dynamic infusion cavernosometry and cavernosography (DICC). Patie nts with suspected impotence were evaluated from 1992 - 1996. Patient ages ranged from 24 - 75 y (mean 48 y), Eighteen men had arteriogenic impotence diagnosed by abnormal penile duplex ultrasound after injection of a vasoact ive agent, and 23 men had venous leakage diagnosed by DICC, Results: Eighteen men with arteriogenic impotence had the following mean bl ood gas values: pH = 7.38 +/- 0.01, PCO2 = 45.50 +/- 0.94, PO2 = 65.17 +/- 2.16, Twenty-three men with venogenic (venous leak) impotence had the follo wing mean cavernosal blood gas values: pH = 7.41 +/- 0.01, PCO2 = 42.26 +/- 0.83, PO2 = 74.17 +/- 2.51, The differences in PO2 were significant (P < 0 .05), A subgroup of men with severe venous leakage had PO2 values that were similar to the low arterial P02 values. Conclusion: The low P02 in patients with arteriogenic impotence, and the su bset of men with severe venous leak impotence, support a global concept of low cavernosal P02 as a mechanism for both arteriogenic and venogenic impot ence.