INFLUENCE OF DIFFERENT FACTORS ON HEART-R ATE-VARIABILITY IN PATIENTSWITH ARTERIAL-HYPERTENSION

The purpose of this study was to evaluate tile influence of different factors, among them left ventricular hypertrophy (LVH) on long-term he art rate variability (HRV) in patients with hypertension. 38 patients with arterial hypertension of different genesis were included in the s tudy. Ischemia was excluded in all the patients by the data of clinica l and instrumental methods of investigation. LVH data obtained from HR V of 20 hearthy subjects was used as control. HRV was evaluated by est imating variations for short intervals of a rhythmogram (VSI). A HRV d ecrease did not depend on sex, but essentially depended on patients'a age, disease duration and the form of hypertension. A marked tendency leading to the rate variability decrease was observed only in moderate LVH. In cases of original LVH variability data did not differ from th ose in patients without signs of LVH. Low or marginal HRV was more oft en observed in patients with essential hypertension and in those with hypertension of endocrine genesis, As far as renal hypertension is con cerned low variability was less frequent. There were a lot of factors which affect the change of HRV, The more significant of them were the patients' age, hypertension genesis and form of hypertension. Factors loading to tile rate variability decrease were the following: age abov e 40, endocrinic or essential hypertension and moderate form of hypert ension.