INFLUENCE OF A NEW INHIBITOR OF ANGIOTENS IN-CONVERTING ENZYME MOEXIPRIL ON CIRCADIAN-RHYTHMS OF ARTERIAL-PRESSURE IN HYPERTENSIVE SUBJECTS

Authors
OLBINSKAYA LI ANDRUSCHISHINA TB
Citation
Li. Olbinskaya et Tb. Andruschishina, INFLUENCE OF A NEW INHIBITOR OF ANGIOTENS IN-CONVERTING ENZYME MOEXIPRIL ON CIRCADIAN-RHYTHMS OF ARTERIAL-PRESSURE IN HYPERTENSIVE SUBJECTS, Terapevticeskij arhiv, 69(3), 1997, pp. 58-61
Citations number
9
Categorie Soggetti
Medicine, General & Internal
Journal title
Terapevticeskij arhiv → ACNP
ISSN journal
00403660
Volume
69
Issue
3
Year of publication
1997
Pages
58 - 61
Database
ISI
SICI code
0040-3660(1997)69:3<58:IOANIO>2.0.ZU;2-O
Abstract
24-hour monitoring of arterial pressure was performed before, 3 and 9 weeks after moexipril treatment (daily dose 7.5-15 mg) for mild and mo derate hypertension. Of 15 patients treated 66.6% responded to the 9-w eek course. Adjuvant hypothiazid elevated the effect to 73.6%. Moexipr il lowered mean 24-h diastolic pressure without changing the 24-h pres sure curve or heart rate. Antihypertensive moexipril effect was higher in the day time. Variability of diastolic arterial pressure was lower at night.